DNA Binding Motif

						

			
Accessions: TEAD4_PITX1_2_3_4_5 (HumanTF2 1.0)

			
Names: TEAD4_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCATwCCdyacTAATCC
Weblogo: 
PSSM: P0      A      C      G      T
01    323     15    162     11      r
02     41    485     28     12      C
03    485      0      0      1      A
04     25      0      0    485      T
05    271      0     42    485      w
06     27    485     20     11      C
07      6    420      5     54      C
08    123     57    155    151      d
09     90    152     72    171      y
10    175     91    115    104      a
11     68    200    103    114      c
12     20      3      0    485      T
13    485     16     64     36      A
14    485      8      6     17      A
15      5     49     79    485      T
16     47    485     44     23      C
17     13    485     38     71      C
Type: Heterodimer
Binding TFs: PITX1_TF1 / PITX1_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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