DNA Binding Motif

						

			
Accessions: 6p0s_ABE (3D-footprint 20231221)

			
Names: DNA-binding protein Fis
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ternary DNA complex "FX2" containing E. coli Fis and phage lambda Xis
Length: 16
Consensus: GyCtGTTnnnTAnnCA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      3     26     10     57      y
03      3     71     15      7      C
04      9     19      3     65      t
05      0      0     96      0      G
06      0      0      0     96      T
07     10      7      3     76      T
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11      7      7      7     75      T
12     92      0      3      1      A
13     24     24     24     24      n
14     24     24     24     24      n
15      0     96      0      0      C
16     96      0      0      0      A
Type: Heterodimer
Binding TFs: 6p0s_A (Bacterial regulatory protein, Fis family)
6p0s_B (Bacterial regulatory protein, Fis family)
Binding Sites: 6p0s_C
6p0s_D
			
Publications: Hancock SP, Cascio D, Johnson RC. Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res 47:8874-8887 (2019). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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