DNA Binding Motif
Accessions: | 3wtx_AC (3D-footprint 20231221) |
Names: | Runt-related transcription factor 1 |
Organisms: | Mus musculus, Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Description: | Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA |
Length: | 10 |
Consensus: | GCCACATCCT |
Weblogo: | |
PSSM: | P0 A C G T 01 8 8 72 8 G 02 0 96 0 0 C 03 0 96 0 0 C 04 72 8 8 8 A 05 0 96 0 0 C 06 88 0 8 0 A 07 0 0 8 88 T 08 0 96 0 0 C 09 0 96 0 0 C 10 8 8 8 72 T |
Type: | Heterodimer |
Binding TFs: | 3wtx_C (Ets-domain) 3wtx_A (Runt domain) |
Binding Sites: | 3wtx_D 3wtx_E |
Publications: | Shiina M, Hamada K, Inoue-Bungo T, Shimamura M, Uchiyama A, Baba S, Sato K, Yamamoto M, Ogata K. A Novel Allosteric Mechanism on Protein-DNA Interactions underlying the Phosphorylation-Dependent Regulation of Ets1 Target Gene Expressions. Journal of molecular biology 427:1655-69 (2015). [Pubmed] |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.