DNA Binding Motif

						

			
Accessions: UP00030A_1 (UniPROBE 20160601), UP00069A_1 (UniPROBE 20160601)

			
Names: 1110038H03Rik, 6230403H02Rik, AI836553, end1, Sox-11, Sox11, SRY-box containing gene 11, Transcription factor SOX-11, Sox-1, SOX-1 protein, Sox1, SRY-box containing gene 1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: wkwarAACAAWGraywa
Weblogo: 
PSSM: P0      A      C      G      T
01   0.35   0.24   0.14   0.27      w
02   0.20   0.24   0.28   0.29      k
03   0.35   0.17   0.21   0.27      w
04   0.48   0.11   0.17   0.23      a
05   0.28   0.07   0.48   0.17      r
06   0.86   0.04   0.08   0.01      A
07   0.98      0      0   0.02      A
08   0.01   0.98   0.01   0.01      C
09   0.99      0      0   0.01      A
10   0.99   0.01      0      0      A
11   0.69      0      0   0.30      W
12   0.19      0   0.80   0.01      G
13   0.35   0.07   0.57   0.01      r
14   0.54   0.18   0.19   0.09      a
15   0.20   0.30   0.21   0.29      y
16   0.29   0.20   0.18   0.33      w
17   0.39   0.22   0.15   0.25      a
Type: Heterodimer
Binding TFs: UP00030A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
UP00069A (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor)
Binding Sites: AAACAAAG
AAACAATT
AACAAAGA
AACAATAA
AACAATAG
AACAATTG
AAGACAAT
AATTGTTC
ACAAAGAA
ACAAAGGA
ACAACAAT
ACAATTGT
AGAACAAT
AGACAATA
ATTGTTCA
CATTGTTC
CTTTGTTC
GAACAATA
GACAAAGA
ATTGTCTC
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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