DNA Binding Motif

Accessions: FLI1_FOXI1_1 (HumanTF2 1.0)
Names: FLI1_FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: GAAAACCGAAAM
Weblogo:
PSSM: P0 A C G T
01 279 2 817 77 G
02 817 1 21 3 A
03 817 0 0 0 A
04 817 0 0 0 A
05 817 20 19 0 A
06 6 817 4 0 C
07 3 817 25 0 C
08 0 0 817 4 G
09 817 2 131 0 A
10 817 0 0 131 A
11 817 76 8 153 A
12 233 564 3 17 M
Type: Heterodimer
Binding TFs: FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FOXI1_TF2 (Fork head domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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