DNA Binding Motif

						

			
Accessions: TFAP2C_DRGX (HumanTF2 1.0)

			
Names: TFAP2C_DRGX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: sCCysrGGsrayaATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    108    772    722     64      s
02      0   1494      0     11      C
03      0   1494      0    123      C
04     63    508    221    702      y
05    141    576    682     94      s
06    917    148    429      0      r
07      0      0   1494      2      G
08      9      6   1494     20      G
09      0   1494    795     37      s
10    556    243    460    235      r
11    745    166    372    211      a
12    140    780    147    714      y
13   1494    273    469    138      a
14   1494    320     84     42      A
15     58    171     89   1494      T
16     57    192     13   1494      T
17   1494      0    151    272      A
Type: Heterodimer
Binding TFs: DRGX_TF2 (Homeobox domain)
TFAP2C_TF1 (Transcription factor AP-2)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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