DNA Binding Motif

Accessions: 4uuv_S (3D-footprint 20231221)
Names: ETS TRANSLOCATION VARIANT 4
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the DNA binding ETS domain of human ETV4 in complex with DNA
Length: 6
Consensus: ctTCCG
Weblogo:
PSSM: P0 A C G T
01 13 57 13 13 c
02 16 13 13 54 t
03 0 0 0 96 T
04 0 96 0 0 C
05 0 96 0 0 C
06 0 0 96 0 G
Binding TFs: 4uuv_S (Ets-domain)
Binding Sites: 4uuv_T
4uuv_W
4uuv_X
4uuv_U
Publications: Cooper C.D, Newman J.A, Aitkenhead H, Allerston C.K, Gileadi O. Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation. The Journal of biological chemistry : (2015). [Pubmed]

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