DNA Binding Motif

						

			
Accessions: NHLH2_methyl_1 (HT-SELEX2 May2017)

			
Names: NHLH2
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 18
Consensus: gGGbmkCAGCTGCGyCCc
Weblogo: 
PSSM: P0      A      C      G      T
01   4903   2042  10884   4527      g
02   3015   1046  17600   3001      G
03   1999    240  20495   1566      G
04   2877   6809   6973   5698      b
05  11615  10601    241    104      m
06   2974   3748  11097   8747      k
07      8  22353      8     11      C
08  22353     11     33      7      A
09     14    454  22057    828      G
10    210  21957    590     16      C
11      6     40      9  22347      T
12      0      0  22356      0      G
13   2160  20025    982   4085      C
14    163    130  21031   4105      G
15   1854   8512   2926  13098      y
16   2713  20384    280   1053      C
17   3536  17455    782   1970      C
18   3637  12766   1386   4567      c
Binding TFs: NHLH2 (Helix-loop-helix DNA-binding domain)
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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