DNA Binding Motif

						

			
Accessions: TEAD4_CLOCK_2_3 (HumanTF2 1.0)

			
Names: TEAD4_CLOCK
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: GGwATGygkskvCACGTGk
Weblogo: 
PSSM: P0      A      C      G      T
01    349     51   1265     72      G
02     26     40   1265     42      G
03    877    105      5    388      w
04   1265      6      0     31      A
05     15     60      0   1265      T
06      2     52   1265    195      G
07     38    464     12    751      y
08    272    115    721    157      g
09     98    304    542    321      k
10    162    326    509    268      s
11    110    262    565    328      k
12    354    400    430     81      v
13    106   1265     17     13      C
14   1265      2     34     82      A
15     10   1265      9    176      C
16    105      3   1265      0      G
17     15     51      4   1265      T
18     19      0   1265     69      G
19     48    291    454    472      k
Type: Heterodimer
Binding TFs: CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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