DNA Binding Motif

						

			
Accessions: GCM1_SPDEF_2_3_4 (HumanTF2 1.0)

			
Names: GCM1_SPDEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 25
Consensus: rTrmkGGCGGAtgykgsdTCCGssy
Weblogo: 
PSSM: P0      A      C      G      T
01    232     94    208     93      r
02     53     32     89    465      T
03    237     52    424     13      r
04    149    185     78     72      m
05     39     14    316    158      k
06     10     15    484      5      G
07      8     10    484      5      G
08     21    468     12      8      C
09      0      0    478     10      G
10      6      3    478      6      G
11    480     17      7     14      A
12    137     91     49    321      t
13    148    123    451    119      g
14     35    147     46    257      y
15     77     48    135    225      k
16    119     92    186     88      g
17     80    125    164    115      s
18    182     40    121    141      d
19     13     93      7    470      T
20      3    485      0      0      C
21      4    478     66     25      C
22      3      7    473    114      G
23      8    189    393    104      s
24     55    133    193    103      s
25     62    175     77    170      y
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
SPDEF_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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