DNA Binding Motif

						

			
Accessions: JUNB_2 (HT-SELEX2 May2017), MA1140.2 (JASPAR 2024)

			
Names: JUNB, JUNB(var.2)
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 12
Consensus: gATGACGTCAyc
Weblogo: 
PSSM: P0      A      C      G      T
01     50     46    162     47      g
02    305      7     15      6      A
03      1      1      4    305      T
04      0      0    305     13      G
05    305      1      1      0      A
06      0    305      0      2      C
07      0      1    305      0      G
08      1      3      1    305      T
09     17    305      3      1      C
10    305      2      1      1      A
11      0    114     10    191      y
12     40    187     43     35      c
Type: Heterodimer
Binding TFs: P17275 (bZIP transcription factor, Jun-like transcription factor, Basic region leucine zipper)
JUNB (bZIP transcription factor, Basic region leucine zipper)
P17275
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Ameyar M, Wisniewska M, Weitzman JB. A role for AP-1 in apoptosis: the case for and against. Biochimie 85:747-52 (2003). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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