DNA Binding Motif

						

			
Accessions: ETV5_HES7_2 (HumanTF2 1.0)

			
Names: ETV5_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: gsCrCGyGssbasmGGAwgk
Weblogo: 
PSSM: P0      A      C      G      T
01     25     17     56     12      g
02     20     32     45     14      s
03      7    110      5      0      C
04    110     11     98     16      r
05      1    110      2      4      C
06      1      4    110      2      G
07     19    117      7    110      y
08      4      8    110      7      G
09      5     45     36     24      s
10     20     43     31     16      s
11     17     31     31     30      b
12     34     26     24     27      a
13     51    110    101     22      s
14     50    110     23      0      m
15      8      0    110      0      G
16      4      7    110      1      G
17    110     15      1     21      A
18    110     33     15     83      w
19     16     24     47     23      g
20     13     26     37     34      k
Type: Heterodimer
Binding TFs: ETV5_TF1 (Ets-domain)
HES7_TF2 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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