DNA Binding Motif

						

			
Accessions: TEAD4_MAX_2 (HumanTF2 1.0)

			
Names: TEAD4_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rCATwCCdhmrrsCACGTG
Weblogo: 
PSSM: P0      A      C      G      T
01    745     58    595     48      r
02    432   1340    128      0      C
03   1340      0    127     22      A
04     45     28      5   1340      T
05    727     36    292   1340      w
06     85   1340    161     96      C
07    121   1340     74    372      C
08    470    163    353    354      d
09    370    342    218    410      h
10    408    336    262    333      m
11    441    248    360    291      r
12    508    219    422    191      r
13    328    413    381    217      s
14      0   1340      3      5      C
15   1340     11     37     13      A
16      0   1340      9     33      C
17     44      0   1340      0      G
18     14      6      8   1340      T
19      0      0   1340      6      G
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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