DNA Binding Motif

						

			
Accessions: SOX4_2 (HT-SELEX2 May2017), MA0867.2 (JASPAR 2024)

			
Names: SOX4
Organisms: Homo sapiens, Mus musculus
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 10
Consensus: gaACAAwGrv
Weblogo: 
PSSM: P0      A      C      G      T
01   3190   1771   5582   2286      g
02   5582    951   2047    431      a
03   5582      0      0      9      A
04      0   5582     37     33      C
05   5582      1      6      0      A
06   5582      6     11      0      A
07   5582    120     50   2719      w
08   1018     64   5582     83      G
09   2093   1422   3489    174      r
10   1775   1438   1889    480      v
Type: Heterodimer
Binding TFs: Q06945 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
SOX4 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Q06945
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Stros M, Launholt D, Grasser KD. The HMG-box: a versatile protein domain occurring in a wide variety of DNA-binding proteins. Cell Mol Life Sci : (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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