DNA Binding Motif

						

			
Accessions: TEAD4_EOMES_1 (HumanTF2 1.0)

			
Names: TEAD4_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: ggyGybAMATwcytwtcrCrCy
Weblogo: 
PSSM: P0      A      C      G      T
01    121    117    229    152      g
02    118    199    619     93      g
03     43    233      1    386      y
04     43      0    619      0      G
05    132    218     61    208      y
06    129    175    158    158      b
07    619     14     84     19      A
08    172    448      0      6      M
09    619     51      8     31      A
10     21      0     13    619      T
11    225      0    106    394      w
12    185    619     89     83      c
13     29    391      0    228      y
14    104    152    135    228      t
15    198    103    100    218      w
16    149    164     21    619      t
17    194    425    167    151      c
18    405     28    214     47      r
19      7    619     25     57      C
20    350      0    269     41      r
21    114    619     95     72      C
22    121    179    150    169      y
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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