DNA Binding Motif

						

			
Accessions: 6wc2_D (3D-footprint 20231221)

			
Names: MEF2 Chimera,Myocyte-specific enhancer factor 2B,Myocyte-specific enhancer factor 2A
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex
Length: 5
Consensus: caCTA
Weblogo: 
PSSM: P0      A      C      G      T
01     16     54     13     13      c
02     54     16     13     13      a
03      0     96      0      0      C
04      0      0      0     96      T
05     96      0      0      0      A
Binding TFs: 6wc2_D (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 6wc2_G
6wc2_H
			
Publications: Lei X, Zhao J, Sagendorf JM, Rajashekar N, Xu J, Dantas Machado AC, Sen C, Rohs R, Feng P, Chen L. Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface. J Mol Biol 432:5499-5508 (2020). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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