DNA Binding Motif

Accessions: 1f5t_ABCD (3D-footprint 20231221)
Names: DIPHTHERIA TOXIN REPRESSOR
Organisms: Corynebacterium diphtheriae, strain ATCC 700971 / NCTC 13129 / Biotype gravis
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE
Length: 15
Consensus: AGGTtAGCCTaACnT
Weblogo:
PSSM: P0 A C G T
01 96 0 0 0 A
02 8 8 72 8 G
03 0 0 96 0 G
04 0 0 0 96 T
05 8 16 16 56 t
06 96 0 0 0 A
07 0 0 96 0 G
08 0 96 0 0 C
09 0 96 0 0 C
10 0 0 0 96 T
11 48 16 16 16 a
12 96 0 0 0 A
13 0 96 0 0 C
14 24 24 24 24 n
15 0 0 0 96 T
Binding TFs: 1f5t_A / 1f5t_B / 1f5t_C / 1f5t_D (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain)
Binding Sites: 1f5t_E
1f5t_F
Publications: Chen C.S, White A, Love J, Murphy J.R, Ringe D. Methyl groups of thymine bases are important for nucleic acid recognition by DtxR. Biochemistry 39:10397-407 (2000). [Pubmed]

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