DNA Binding Motif

Accessions: UP00049A_1 (UniPROBE 20160601)
Names: nuclear antigen Sp100, Nuclear autoantigen Sp-100, Nuclear dot-associated Sp100 protein, Sp100, Speckled 100 kDa
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 14
Consensus: rwTwtmCGgAAAwt
Weblogo:
PSSM: P0 A C G T
01 0.40 0.13 0.34 0.13 r
02 0.32 0.03 0.06 0.59 w
03 0.16 0.03 0.04 0.77 T
04 0.27 0.15 0.04 0.54 w
05 0.22 0.24 0.17 0.36 t
06 0.31 0.30 0.17 0.22 m
07 0 0.99 0.01 0 C
08 0 0.12 0.87 0 G
09 0.09 0.09 0.59 0.23 g
10 0.78 0.08 0.06 0.08 A
11 0.87 0.01 0.03 0.09 A
12 0.71 0.05 0.03 0.22 A
13 0.49 0.14 0.10 0.28 w
14 0.19 0.11 0.21 0.49 t
Binding TFs: UP00049A (SAND domain)
Binding Sites: AACGACGA
AATCGCGA
AATTTCCG
ATATCGCG
ATTCCGCG
ATTGCGCG
ATTTCCGG
ATTTCGCG
ATTTTCCG
CGCGAAAA
CGCGACAA
CGCGCAAA
CGTCGAAA
GATTTCGC
GTCGTTTA
TACGGAAA
TATCGCGA
TCGCGAAA
TCGCGTAA
TTCCGGAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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