DNA Binding Motif

Accessions: FLI1_FOXI1_2 (HumanTF2 1.0), UN0530.1 (JASPAR 2024)
Names: FLI1_FOXI1, FLI1::FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 13
Consensus: rcCGGAWGTTkay
Weblogo:
PSSM: P0 A C G T
01 2125 607 1532 1183 r
02 937 3657 1195 370 c
03 522 3657 0 0 C
04 0 2 3657 12 G
05 0 18 3657 29 G
06 3657 8 3 8 A
07 1697 2 21 3657 W
08 446 6 3657 11 G
09 41 139 9 3657 T
10 247 65 559 3657 T
11 284 25 1277 2380 k
12 2879 495 372 778 a
13 230 2244 967 1413 y
Type: Heterodimer
Binding TFs: FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FOXI1_TF2 (Fork head domain)
Q12952 (Fork head domain)
Q12952
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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