DNA Binding Motif

						

			
Accessions: 4ond_A (3D-footprint 20231221)

			
Names: Ancestral SR2 Helix Mutant
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Ancestral Steroid Receptor 2 DBD helix mutant - ERE DNA complex
Length: 4
Consensus: gtCA
Weblogo: 
PSSM: P0      A      C      G      T
01     12     12     60     12      g
02     12     12     12     60      t
03      0     96      0      0      C
04     84      0      0     12      A
Binding TFs: 4ond_A (Zinc finger, C4 type (two domains))
Binding Sites: 4ond_I
4ond_J
			
Publications: McKeown A.N, Bridgham J.T, Anderson D.W, Murphy M.N, Ortlund E.A, Thornton J.W. Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell 159:58-68 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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