DNA Binding Motif

						

			
Accessions: 2nll_AB (3D-footprint 20231221)

			
Names: PROTEIN (RETINOIC ACID RECEPTOR)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
Length: 15
Consensus: GGtnAnnnnaGGTCA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0     80     16      G
03      5     21     10     60      t
04     24     24     24     24      n
05     96      0      0      0      A
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     64     10     10     12      a
11      0      0     96      0      G
12      0      0     96      0      G
13      0      6      5     85      T
14      0     96      0      0      C
15     76      5     10      5      A
Type: Heterodimer
Binding TFs: 2nll_A (Zinc finger, C4 type (two domains))
2nll_B (Zinc finger, C4 type (two domains))
Binding Sites: 2nll_D
2nll_C
			
Publications: Rastinejad F., Perlmann T., Evans R. M., Sigler P. B. Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature 375:203-211 (1995). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.