DNA Binding Motif

						

			
Accessions: 4bqa_ADG (3D-footprint 20231221)

			
Names: PROTEIN C-ETS-2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the ETS domain of human ETS2 in complex with DNA
Length: 25
Consensus: TTCCGnnnnCGGAAGnnnnCTTCCG
Weblogo: 
PSSM: P0      A      C      G      T
01      4      4      6     82      T
02      0      0      0     96      T
03      0     96      0      0      C
04      0     96      0      0      C
05      0      0     96      0      G
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10      5     87      4      0      C
11      0      0     96      0      G
12      0      0     96      0      G
13     96      0      0      0      A
14     78     10      4      4      A
15      8      4     78      6      G
16     24     24     24     24      n
17     24     24     24     24      n
18     24     24     24     24      n
19     24     24     24     24      n
20      4     74     14      4      C
21      6      4      4     82      T
22      0      0      0     96      T
23      0     96      0      0      C
24      0     96      0      0      C
25      4      4     87      1      G
Type: Heterodimer
Binding TFs: 4bqa_A (Ets-domain)
4bqa_D (Ets-domain)
4bqa_G (Ets-domain)
Binding Sites: 4bqa_B
4bqa_C
			
Publications: Newman J.A, Cooper C.D, Aitkenhead H, Gileadi O. Structural insights into the autoregulation and cooperativity of the human transcription factor ets-2. The Journal of biological chemistry 290:8539-49 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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