DNA Binding Motif
| Accessions: | UP00521A_4 (UniPROBE 20160601), UP00532A_2 (UniPROBE 20160601) |
| Names: | FOXN2, HTLF, Human T-cell leukemia virus enhancer factor, FoxN2-3_Tadh, T.adh FoxN2/3 |
| Organisms: | Homo sapiens, Trichoplax adhaerens |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 22 |
| Consensus: | gakwwyrTGTAwACAAwmywab |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.23 0.21 0.40 0.16 g 02 0.36 0.18 0.23 0.24 a 03 0.22 0.16 0.29 0.33 k 04 0.41 0.11 0.12 0.36 w 05 0.44 0.17 0.11 0.28 w 06 0.16 0.30 0.21 0.33 y 07 0.38 0.16 0.30 0.16 r 08 0.02 0.10 0.05 0.83 T 09 0.23 0.01 0.76 0.01 G 10 0.01 0.01 0 0.97 T 11 0.95 0.03 0 0.02 A 12 0.61 0.04 0.01 0.34 w 13 0.97 0.01 0.01 0.02 A 14 0.01 0.94 0.01 0.05 C 15 0.95 0.01 0.01 0.03 A 16 0.70 0.09 0.11 0.10 A 17 0.51 0.09 0.08 0.32 w 18 0.28 0.43 0.08 0.20 m 19 0.10 0.28 0.10 0.51 y 20 0.33 0.14 0.03 0.50 w 21 0.54 0.24 0.05 0.17 a 22 0.19 0.25 0.27 0.29 b |
| Type: | Heterodimer |
| Binding TFs: | UP00521A (Fork head domain) UP00532A (Fork head domain) |
| Binding Sites: | GTAAACAA ATAAACAA ATTGTTTA GACGCGTC TAAACAAA TGTAAACA TGTATACA AAAGACGC AAAGCGTC AAGCGTCC ACCGCGTC AGACGCCA AGACGCTA AGCGTCAT AGCGTCCC AGCGTCCT AGGACGCG AGGGACGC ATAGCGTC ATCGCGTC ATGGCGTC CCGCGTCC CGACGCTA GACGCCAA GACGCTAA GACGCTAC GAGACGCC GGACGCTA TAGCGTCA |
| Publications: | Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed] |
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