DNA Binding Motif

Accessions: 3r8f_ABCD (3D-footprint 20231221)
Names: Chromosomal replication initiator protein dnaA
Organisms: Aquifex aeolicus, strain VF5
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Replication initiator DnaA bound to AMPPCP and single-stranded DNA
Length: 10
Consensus: AnnAnnanna
Weblogo:
PSSM: P0 A C G T
01 96 0 0 0 A
02 24 24 24 24 n
03 24 24 24 24 n
04 96 0 0 0 A
05 24 24 24 24 n
06 24 24 24 24 n
07 54 13 16 13 a
08 24 24 24 24 n
09 24 24 24 24 n
10 54 16 13 13 a
Binding TFs: 3r8f_A / 3r8f_B / 3r8f_C / 3r8f_D (ATPase family associated with various cellular activities (AAA), Bacterial dnaA protein, IstB-like ATP binding protein, Bacterial dnaA protein helix-turn-helix)
Binding Sites: 3r8f_E
Publications: Duderstadt K.E, Chuang K, Berger J.M. DNA stretching by bacterial initiators promotes replication origin opening. Nature 478:209-13 (2011). [Pubmed]

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