DNA Binding Motif
Accessions: | MEIS1_HOXB13 (HumanTF2 1.0) |
Names: | MEIS1_HOXB13 |
Organisms: | Homo sapiens |
Libraries: | HumanTF2 1.0 1 1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed] |
Notes: | Site type: heterodimeric; Experiment type: CAP-SELEX |
Length: | 15 |
Consensus: | symrTwAAmcTGTCa |
Weblogo: | |
PSSM: | P0 A C G T 01 2052 3797 2837 639 s 02 594 3668 291 2965 y 03 3414 3220 721 1765 m 04 3466 518 3168 510 r 05 42 491 36 6634 T 06 6634 199 1088 2775 w 07 6634 61 39 908 A 08 6634 822 109 670 A 09 2392 2154 1199 890 m 10 2920 6634 3170 587 c 11 469 1966 191 6634 T 12 724 32 6634 126 G 13 565 1658 78 6634 T 14 33 6634 20 120 C 15 6634 1027 1577 1976 a |
Type: | Heterodimer |
Binding TFs: | HOXB13_TF1 / HOXB13_TF2 (Homeobox domain) MEIS1_TF1 (Homeobox domain, Homeobox KN domain) HOXB13_Full (Homeobox domain, Hox protein A13 N terminal) MEIS1_Crystal (Homeobox domain, Homeobox KN domain) |
Publications: | Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed] |
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