DNA Binding Motif

						

			
Accessions: MA0852.2 (JASPAR 2024)

			
Names: FOXK1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 14
Consensus: wrkGTAAACAagsv
Weblogo: 
PSSM: P0      A      C      G      T
01    329    184    258    285      w
02    416    175    270    195      r
03    247    142    272    395      k
04    143     28    868     17      G
05     60      5     44    947      T
06   1003     37     10      6      A
07    999     37     11      9      A
08   1022     13     10     11      A
09     10    958     12     76      C
10   1015     16     12     13      A
11    512    199    204    141      a
12    185    201    568    102      g
13    242    269    362    183      s
14    283    288    270    215      v
Type: Heterodimer
Binding TFs: P85037 (Fork head domain, FHA domain)
P85037
Binding Sites: MA0852.2.1
MA0852.2.10
MA0852.2.11
MA0852.2.12
MA0852.2.13
MA0852.2.14
MA0852.2.15
MA0852.2.16
MA0852.2.17
MA0852.2.18
MA0852.2.19
MA0852.2.2
MA0852.2.20
MA0852.2.3
MA0852.2.4
MA0852.2.5
MA0852.2.6
MA0852.2.7
MA0852.2.8
MA0852.2.9
			
Publications: Tsai K.L, Huang C.Y, Chang C.H, Sun Y.J, Chuang W.J, Hsiao C.D. Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins. The Journal of biological chemistry 281:17400-9 (2006). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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