DNA Binding Motif

Accessions: 3a01_AB (3D-footprint 20231221)
Names: Homeodomain-containing protein
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Aristaless and Clawless homeodomains bound to DNA
Length: 11
Consensus: TTAATTAATTG
Weblogo:
PSSM: P0 A C G T
01 5 10 5 76 T
02 5 5 6 80 T
03 96 0 0 0 A
04 96 0 0 0 A
05 5 6 10 75 T
06 6 5 5 80 T
07 96 0 0 0 A
08 96 0 0 0 A
09 5 1 5 85 T
10 5 6 5 80 T
11 0 0 96 0 G
Type: Heterodimer
Binding TFs: 3a01_A (Homeobox domain)
3a01_B (Homeobox domain)
Binding Sites: 3a01_C
3a01_D
Publications: Miyazono K, Zhi Y, Takamura Y, Nagata K, Saigo K, Kojima T, Tanokura M. Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless. The EMBO journal 29:1613-23 (2010). [Pubmed]

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