DNA Binding Motif

Accessions: GCM1_HOXA13 (HumanTF2 1.0)
Names: GCM1_HOXA13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: rTGcGGGTmaTaAa
Weblogo:
PSSM: P0 A C G T
01 568 119 335 36 r
02 40 61 109 794 T
03 237 47 667 3 G
04 111 544 138 111 c
05 86 17 904 24 G
06 20 27 904 11 G
07 16 19 904 1 G
08 20 88 30 766 T
09 550 257 46 50 m
10 904 42 342 108 a
11 77 83 42 904 T
12 904 84 179 287 a
13 904 100 105 107 A
14 904 116 375 137 a
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
HOXA13_TF2 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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