DNA Binding Motif

						

			
Accessions: TEAD4_HOXB13_1 (HumanTF2 1.0)

			
Names: TEAD4_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: mtyGTAAAATGyg
Weblogo: 
PSSM: P0      A      C      G      T
01    162    334    146      2      m
02     55     90     33    334      t
03     68    334     16    220      y
04     95      4    334      0      G
05      9      0      1    334      T
06    334      8     58     85      A
07    334      0      0     46      A
08    334      4      0     25      A
09    334     19      0      0      A
10     19     53     14    334      T
11      9     25    334     37      G
12     10    233     14    101      y
13     72     71    154     38      g
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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