DNA Binding Motif

						

			
Accessions: 1kb4_AB (3D-footprint 20231221)

			
Names: Vitamin D3 Receptor
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of VDR DNA-binding Domain Bound to a Canonical Direct Repeat with Three Base Pair Spacer (DR3) Response Element
Length: 13
Consensus: GGncAnnnrGGnC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0     96      0      G
03     24     24     24     24      n
04     16     56      8     16      c
05     72      8      8      8      A
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09     24      8     56      8      r
10      0      0     96      0      G
11      0      0     96      0      G
12     24     24     24     24      n
13      0     96      0      0      C
Type: Heterodimer
Binding TFs: 1kb4_A (Zinc finger, C4 type (two domains))
1kb4_B (Zinc finger, C4 type (two domains))
Binding Sites: 1kb4_C
1kb4_D
			
Publications: Shaffer P.L, Gewirth D.T. Structural basis of VDR-DNA interactions on direct repeat response elements. The EMBO journal 21:2242-52 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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