DNA Binding Motif

						

			
Accessions: 2r5y_AB (3D-footprint 20231221)

			
Names: Homeotic protein Sex combs reduced
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of Scr/Exd complex bound to a consensus Hox-Exd site
Length: 10
Consensus: TGATTTAwgG
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      0      0     96      0      G
03     96      0      0      0      A
04      0      0      0     96      T
05      0      0      0     96      T
06      0      0      0     96      T
07     96      0      0      0      A
08     27     13     15     41      w
09     16     13     54     13      g
10      0      0     96      0      G
Type: Heterodimer
Binding TFs: 2r5y_A (Homeobox domain)
2r5y_B (Homeobox domain, Homeobox KN domain)
Binding Sites: 2r5y_C
2r5y_D
			
Publications: Joshi R, Passner J.M, Rohs R, Jain R, Sosinsky A, Crickmore M.A, Jacob V, Aggarwal A.K, Honig B, Mann R.S. Functional specificity of a Hox protein mediated by the recognition of minor groove structure. Cell 131:530-43 (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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