DNA Binding Motif

						

			
Accessions: ETV2_DLX2_2 (HumanTF2 1.0)

			
Names: ETV2_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rsMGGAAryvvsyaATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    299     78    181     95      r
02    154    480    240     75      s
03    173    480     20      0      M
04      1      0    480      1      G
05      0      0    480      0      G
06    480      6      0      5      A
07    480     30      2    127      A
08    156     83    212     29      r
09     87    137     70    186      y
10    136    122    147     75      v
11    151    129    139     61      v
12     89    141    188     62      s
13     36    314     32    166      y
14    480    169    115    121      a
15    480    135     29     44      A
16     11     26      3    480      T
17     20     93     20    480      T
18    480     26     95    105      A
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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