DNA Binding Motif

						

			
Accessions: Esrra_DBD_2 (HumanTF 1.0), MA0592.2 (JASPAR 2024)

			
Names: Esrra
Organisms: Mus musculus
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 11
Consensus: tTCAAGGTCAT
Weblogo: 
PSSM: P0      A      C      G      T
01    110    696   1482   4775      t
02    131    339     57   4775      T
03     33   4775    404      4      C
04   4775      0      4      0      A
05   4775      0      4      0      A
06      1      3   4775      9      G
07      0      2   4775      3      G
08      6     11     52   4775      T
09      0   4775    211     42      C
10   4775      6    293      2      A
11    739    350     55   3630      T
Type: Heterodimer
Binding TFs: O08580 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
Esrra_DBD (Zinc finger, C4 type (two domains))
O08580
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Dufour C. R., Wilson B. J., Huss J. M., Kelly D. P., Alaynick W. A., Downes M., Evans R. M., Blanchette M., Giguere V. Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.. Cell Metab. 5:345-356 (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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