DNA Binding Motif

Accessions: MA1994.1 (JASPAR 2024)
Names: Nkx2-1
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 13
Consensus: rvCACTTGArmwh
Weblogo:
PSSM: P0 A C G T
01 5220 3094 4172 3756 r
02 4407 5386 4386 2063 v
03 289 14886 181 886 C
04 15478 275 146 343 A
05 168 15640 118 316 C
06 369 162 605 15106 T
07 252 518 315 15157 T
08 895 657 14172 518 G
09 15245 243 213 541 A
10 8275 2595 4157 1215 r
11 5203 5568 2412 3059 m
12 4394 3539 3099 5210 w
13 4091 4206 3214 4731 h
Type: Heterodimer
Binding TFs: P50220 (Homeobox domain)
P50220
Binding Sites: MA1994.1.1 / MA1994.1.3
MA1994.1.10 / MA1994.1.15
MA1994.1.11 / MA1994.1.17
MA1994.1.12 / MA1994.1.18
MA1994.1.13 / MA1994.1.20
MA1994.1.14
MA1994.1.15
MA1994.1.16
MA1994.1.17
MA1994.1.18
MA1994.1.19
MA1994.1.2 / MA1994.1.4
MA1994.1.20
MA1994.1.3
MA1994.1.4 / MA1994.1.5
MA1994.1.5 / MA1994.1.6
MA1994.1.6 / MA1994.1.7
MA1994.1.7 / MA1994.1.8
MA1994.1.8 / MA1994.1.9
MA1994.1.10 / MA1994.1.9
MA1994.1.1
MA1994.1.11
MA1994.1.12
MA1994.1.13
MA1994.1.14
MA1994.1.16
MA1994.1.19
MA1994.1.2
Publications: Clarke N, Biscocho J, Kwei KA, Davidson JM, Sridhar S, Gong X, Pollack JR. Integrative Genomics Implicates EGFR as a Downstream Mediator in NKX2-1 Amplified Non-Small Cell Lung Cancer. PLoS One : (2015). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.