DNA Binding Motif

Accessions: TEAD4_ELK1_2_3_4 (HumanTF2 1.0)
Names: TEAD4_ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: GGAATsCGGAAGtk
Weblogo:
PSSM: P0 A C G T
01 14 2 80 4 G
02 5 0 94 10 G
03 94 19 3 6 A
04 94 2 0 6 A
05 0 0 17 94 T
06 0 35 59 2 s
07 3 94 3 4 C
08 0 3 94 8 G
09 2 0 94 5 G
10 94 0 0 0 A
11 94 5 1 25 A
12 16 23 94 0 G
13 8 18 11 76 t
14 21 5 34 34 k
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
TEAD4_TF1 (TEA/ATTS domain family)
ELK1_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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