DNA Binding Motif

						

			
Accessions: 3jr9_AB (3D-footprint 20231221)

			
Names: DNA-binding protein fis
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Fis bound to 27 bp optimal binding sequence F2
Length: 17
Consensus: TGTnGAnnnnnTCnGCA
Weblogo: 
PSSM: P0      A      C      G      T
01      4      4      6     82      T
02      0      0     96      0      G
03      0      6      8     82      T
04     24     24     24     24      n
05      4      4     75     13      G
06     82      4      6      4      A
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12      5      0      4     87      T
13      4     75     13      4      C
14     24     24     24     24      n
15      0      0     96      0      G
16      0     96      0      0      C
17     84      4      4      4      A
Type: Heterodimer
Binding TFs: 3jr9_A (Bacterial regulatory protein, Fis family)
3jr9_B (Bacterial regulatory protein, Fis family)
Binding Sites: 3jr9_C
3jr9_D
			
Publications: Stella S, Cascio D, Johnson R.C. The shape of the DNA minor groove directs binding by the DNA-bending protein Fis. Genes & development 24:814-26 (2010). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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