DNA Binding Motif

						

			
Accessions: GCM2_DRGX_1 (HumanTF2 1.0), UN0551.1 (JASPAR 2024)

			
Names: GCM2_DRGX, GCM2::DRGX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 14
Consensus: rTrsGGGtaATTag
Weblogo: 
PSSM: P0      A      C      G      T
01   2040    253    840    138      r
02    140    208    235   2880      T
03   1241    205   1639      0      r
04    528   1961    919    207      s
05    192     27   2880    302      G
06      0      0   2880     24      G
07     28      6   2880     43      G
08    310    544    164   1861      t
09   2880    879    773   1238      a
10   2880    245    262    273      A
11    220     77    449   2880      T
12    513    319    190   2880      T
13   2880    135    392    941      a
14    645    461   1092    682      g
Type: Heterodimer
Binding TFs: O75603 (GCM motif protein)
DRGX_TF2 (Homeobox domain)
GCM2_TF1 (GCM motif protein)
O75603
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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