DNA Binding Motif

						

			
Accessions: TFAP4_ETV4 (HumanTF2 1.0)

			
Names: TFAP4_ETV4
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rsCGGAwvCAgsTGkb
Weblogo: 
PSSM: P0      A      C      G      T
01    417    180    315    107      r
02    213    731    708    107      s
03    190    731     64     25      C
04     18      0    731     10      G
05      3     38    731     13      G
06    731     12      9     42      A
07    731     78     49    521      w
08    328    273    403     49      v
09      8    731      4      6      C
10    731     24    116     23      A
11     22    170    561    158      g
12    235    397    334     22      s
13     38     70     57    731      T
14     12     23    731     20      G
15    118    146    242    225      k
16    123    190    218    201      b
Type: Heterodimer
Binding TFs: ETV4_TF2 (Ets-domain)
TFAP4_TF1 (Helix-loop-helix DNA-binding domain)
TFAP4_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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