DNA Binding Motif

						

			
Accessions: MA0738.2 (JASPAR 2024)

			
Names: HIC2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 6
Consensus: rTGCCM
Weblogo: 
PSSM: P0      A      C      G      T
01   2606    394   2285    367      r
02      0    117      0   4891      T
03    494    354   4891    151      G
04     23   4891     14      0      C
05    435   4891      0     59      C
06   1466   3425      0      0      M
Type: Heterodimer
Binding TFs: Q96JB3 (Zinc finger, C2H2 type, BTB/POZ domain, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q96JB3
			
Publications: Pinte S., Stankovic-Valentin N., Deltour S., Rood B. R., Guerardel C., Leprince D. The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties.. J. Biol. Chem. 279:38313-38324 (2004). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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