DNA Binding Motif

						

			
Accessions: TEAD4_DLX2_2_3_4_5_6 (HumanTF2 1.0)

			
Names: TEAD4_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: crCATwCCrvsyaATTA
Weblogo: 
PSSM: P0      A      C      G      T
01     67    169     66     93      c
02    241     26    154     12      r
03     49    395     43      0      C
04    395      3     25      2      A
05     19     12      3    395      T
06    256      6     87    395      w
07     35    395      0     18      C
08     27    312      2     53      C
09    138     71    111     74      r
10    109    113    110     63      v
11     73    165    103     53      s
12     31    264     14    130      y
13    395    173     67     58      a
14    395     74     19     22      A
15     80     13      0    395      T
16     22     66     15    395      T
17    350      6     19     19      A
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
TEAD4_TF1 (TEA/ATTS domain family)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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