DNA Binding Motif

						

			
Accessions: TEAD4_HOXA3_2 (HumanTF2 1.0)

			
Names: TEAD4_HOXA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCATwCCrmmcymATTA
Weblogo: 
PSSM: P0      A      C      G      T
01   7195    409   5038    239      r
02   1397  12233    271     13      C
03  12233     34    259      3      A
04      0     19     45  12233      T
05   8163     26   1037  12233      w
06    115  12233    264    171      C
07    232  10438      0   1571      C
08   4928   2079   3356   1869      r
09   3894   3921   1804   2613      m
10   3631   3376   2510   2715      m
11   1783   6147   2750   1552      c
12   1762   5054   1040   4376      y
13   5457  12233   1800    940      m
14  12233    112   1572      0      A
15      0     29      0  12233      T
16    289   1483    125  12233      T
17  12233    347    247    649      A
Type: Heterodimer
Binding TFs: TEAD4_TF1 (TEA/ATTS domain family)
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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