DNA Binding Motif

						

			
Accessions: GCM2_TEF (HumanTF2 1.0)

			
Names: GCM2_TEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rTrsGGGykgrTTAyRTAA
Weblogo: 
PSSM: P0      A      C      G      T
01    471     65    230      0      r
02     11      0     64    701      T
03    221      8    480      8      r
04     58    701    291    101      s
05      0     32    701     94      G
06      0      0    701      0      G
07      6      7    701      6      G
08     20    209    116    356      y
09     50     44    293    314      k
10     90     37    446    127      g
11    247    156    299      0      r
12      0      0      0    701      T
13      0      6     99    701      T
14    701      0     55     32      A
15      5    701      0    367      y
16    262     13    701      0      R
17     10     32      5    701      T
18    701     19     17      0      A
19    701      0      0     14      A
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
TEF_TF1 / TEF_TF2 (bZIP transcription factor, Basic region leucine zipper)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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