DNA Binding Motif

						

			
Accessions: E2F3_FOXO6_1 (HumanTF2 1.0)

			
Names: E2F3_FOXO6
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: gaaTGACACGCGCCCmc
Weblogo: 
PSSM: P0      A      C      G      T
01    152    126    232    100      g
02    474     92    110     51      a
03    480    176     40    135      a
04     73     69     42    587      T
05      0     54    606     59      G
06    611      0      6     15      A
07      7    613     15    125      C
08    606     29     17      6      A
09      1    598     41      0      C
10     16     67    607      1      G
11     37    613     55      9      C
12     29     62    602     36      G
13    122    585      8      0      C
14     21    609      1     23      C
15     79    516     19      6      C
16    315    169     58     68      m
17     77    377     76     81      c
Type: Heterodimer
Binding TFs: FOXO6_TF2 (Fork head domain)
E2F3_TF1 (E2F/DP family winged-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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