DNA Binding Motif

Accessions: POU2F1_ELK1_2 (HumanTF2 1.0), UN0578.1 (JASPAR 2024)
Names: POU2F1_ELK1, POU2F1::ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 13
Consensus: mCCGsATATGCAm
Weblogo:
PSSM: P0 A C G T
01 236 150 53 0 m
02 40 436 69 30 C
03 0 436 20 26 C
04 21 0 436 0 G
05 196 229 436 0 s
06 436 2 12 21 A
07 132 4 0 436 T
08 436 0 8 82 A
09 0 43 17 436 T
10 0 0 436 0 G
11 59 436 9 21 C
12 436 13 87 63 A
13 185 147 0 104 m
Type: Heterodimer
Binding TFs: P19419 (Ets-domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
ELK1_TF1 (Ets-domain)
P19419
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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