DNA Binding Motif

						

			
Accessions: 5zfy_A (3D-footprint 20231221)

			
Names: Double homeobox protein 4-like protein 4
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant
Length: 12
Consensus: CTAATCTntTCA
Weblogo: 
PSSM: P0      A      C      G      T
01      9     72      9      6      C
02      0      0      0     96      T
03     96      0      0      0      A
04     96      0      0      0      A
05      0      9      0     87      T
06      6     67      9     14      C
07      9      4     11     72      T
08     24     24     24     24      n
09      9     16      9     62      t
10      0      0      0     96      T
11      0     96      0      0      C
12     96      0      0      0      A
Binding TFs: 5zfy_A (Homeobox domain, Homeobox KN domain)
Binding Sites: 5zfy_D
5zfy_E
			
Publications: Li Y, Wu B, Liu H, Gao Y, Yang C, Chen X, Zhang J, Chen Y, Gu Y, Li J, Ma J, Gan J. Structural basis for multiple gene regulation by human DUX4. Biochem Biophys Res Commun 505:1161-1167 (2018). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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