DNA Binding Motif

						

			
Accessions: SOX2_full_2 (HumanTF 1.0)

			
Names: SOX2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4; Possible binding to single stranded DNA; < 100 counts
Length: 17
Consensus: hATCAATAmCATTGATm
Weblogo: 
PSSM: P0      A      C      G      T
01     21     25      3     35      h
02     85     15      2      5      A
03      2      6      0     85      T
04      0     85      2      0      C
05     85      0      0      0      A
06     85     21      0      0      A
07      0      0      0     85      T
08     85      0      1     15      A
09     35     25     14     11      m
10      0     85      0      4      C
11     85      0      0      0      A
12      0      0      0     85      T
13      0      0      0     85      T
14      0      0     85      0      G
15     85      0      0      1      A
16      1      6      4     85      T
17     36     29      3     17      m
Binding TFs: SOX2_full (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor)
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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