DNA Binding Motif

						

			
Accessions: 1wet_A (3D-footprint 20231221)

			
Names: PROTEIN (PURINE REPRESSOR)
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: STRUCTURE OF THE PURR-GUANINE-PURF OPERATOR COMPLEX
Length: 8
Consensus: CGAanACg
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0     96      0      G
03     96      0      0      0      A
04     54     16     13     13      a
05     24     24     24     24      n
06     96      0      0      0      A
07      0     96      0      0      C
08     16     13     54     13      g
Binding TFs: 1wet_A (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Sites: 1wet_B
			
Publications: Schumacher M.A, Glasfeld A, Zalkin H, Brennan R.G. The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity. The Journal of biological chemistry 272:22648-53 (1997). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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