DNA Binding Motif

Accessions: ZBTB45_2 (HT-SELEX2 May2017), UN0150.1 (JASPAR 2024)
Names: ZBTB45
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 11
Consensus: kcrCCTATAkm
Weblogo:
PSSM: P0 A C G T
01 241 287 435 636 k
02 289 1598 135 492 c
03 1598 898 1049 133 r
04 17 1598 20 72 C
05 275 1598 314 156 C
06 19 40 0 1598 T
07 1598 0 0 5 A
08 22 49 0 1598 T
09 1598 0 488 16 A
10 12 309 943 656 k
11 641 551 286 120 m
Type: Heterodimer
Binding TFs: ZBTB45 (Zinc finger, C2H2 type, C2H2 type zinc-finger (2 copies), Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q96K62 (Zinc finger, C2H2 type, BTB/POZ domain, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q96K62
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

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