DNA Binding Motif

Accessions: 1sax_A (3D-footprint 20231221)
Names: Methicillin resistance regulatory protein mecI
Organisms: Staphylococcus aureus, strain N315
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Three-dimensional structure of s.aureus methicillin-resistance regulating transcriptional repressor meci in complex with 25-bp ds-DNA
Length: 7
Consensus: TGTAnTA
Weblogo:
PSSM: P0 A C G T
01 9 9 9 69 T
02 0 0 96 0 G
03 0 0 0 96 T
04 67 9 11 9 A
05 24 24 24 24 n
06 0 0 0 96 T
07 67 11 9 9 A
Binding TFs: 1sax_A (MarR family, Penicillinase repressor)
Binding Sites: 1sax_C
1sax_D
Publications: García-Castellanos R, Mallorquí-Fernández G, Marrero A, Potempa J, Coll M, Gomis-Rüth F.X. On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator. The Journal of biological chemistry 279:17888-96 (2004). [Pubmed]

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