DNA Binding Motif

Accessions: MYBL1_FIGLA_2_3_4 (HumanTF2 1.0)
Names: MYBL1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: mCAssTGkwvcmgyAACsGyc
Weblogo:
PSSM: P0 A C G T
01 1359 2311 400 109 m
02 234 4179 18 51 C
03 4179 30 27 23 A
04 16 2211 1968 11 s
05 13 2545 1635 72 s
06 53 65 32 4179 T
07 6 0 4179 80 G
08 157 847 1684 1492 k
09 1115 614 698 1753 w
10 1078 1351 1203 548 v
11 1041 1592 930 616 c
12 1538 1302 519 820 m
13 841 1033 1754 551 g
14 373 1466 289 2714 y
15 4179 61 279 236 A
16 4179 241 178 125 A
17 81 4179 62 80 C
18 249 2240 1939 703 s
19 248 276 4179 471 G
20 771 2069 236 2111 y
21 984 2108 367 721 c
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
MYBL1_TF1 (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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